Grail Computer · research record
Dated experiment record. Statements describe this run, not current submission readiness. Historical H. pylori category names do not establish infection; copy screens are bounded tests. Claims that a source does not exist mean none was identified in that recorded search, not proof of absence. Licensing interpretations in the notes remain unconfirmed. Local access details have been omitted. Current limitations and remaining work.

Q2 tissue-prompt ablation gate

Post-hoc invalidation (2026-08-27): the upstream LoRA was trained with held-out-slide leakage. This remains an exploratory prompt-control record only; it cannot support generalisation or checkpoint selection. See reports/SLIDE_SPLIT_AUDIT_REPORT.md.

Date: 2026-08-26 UTC

Run: 20260826T095638Z-prompt-ablation

Code: 2ed42eb97905706ce7e7b5a97482d85b225c3762

Result: FAIL for tissue-scaffold selection — the curved-object failure is suppressed, but positive-category morphology collapses toward nonspecific tissue

Frozen comparison

This ablation loaded the no-overlay epoch-3 checkpoint with SHA-256 5fb8d73646228a2eb047593113e6c64490c2fe2c6c9c71b803c04b64718e9de7. Width, height, steps, guidance, model, checkpoint, seeds, and normal/metaplasia positive prompts remained fixed. The two H. pylori-positive prompts were changed to request lesion tissue without visible organisms, and the negative prompt was strengthened against worm-like or thick curved objects. Prompt-override SHA-256 was 091d247a1badd4e4e72b0535609bb65eb6322f824ebf4eaa320d9947c99b86a7.

Mechanical, runtime, and privacy results

Morphology finding

The held-out/Q0/Q2-v1/no-overlay/prompt-ablation sheet SHA-256 is fe84106049f0e4cacffdaf68d038486c0384cb7e8079a9d981266359cfca45b3.

Held-out diagnostic SHA-256 is 26fa8a10847aa6f2bed075c9885da791453a70c5c44965fa53c2f71558efbd03.

Gate decision

The experiment identifies a two-part failure: explicit organism wording drives oversized curves, while the existing checkpoint does not retain enough positive-category tissue signal when that wording is removed. The next bounded Q2 correction changes only the 64 positive-category training captions to organism-neutral gastritis and mixed-lesion descriptions. All 128 training pixels, slides, coordinates, provenance, split, model, optimiser, rank, learning rate, epochs, validation seeds, and normal/metaplasia captions remain fixed. Q3 remains blocked.

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