Dated experiment record. Statements describe this run, not current submission readiness. Historical H. pylori category names do not establish infection; copy screens are bounded tests. Claims that a source does not exist mean none was identified in that recorded search, not proof of absence. Licensing interpretations in the notes remain unconfirmed. Local access details have been omitted. Current limitations and remaining work.

FLUX.2 Klein split-corrected normal challenger

Result

FAIL for candidate production. Run 20260827T034257Z-flux2-klein-normal completed successfully on deployed commit 6db7fb3c93242e76202c6d85c3e9d9055b23c536, but no whole checkpoint met the frozen normal-gastric morphology gate. The preregistered stop rule closes the FLUX.2 Klein LoRA path: no second category, final canvas, or candidate pool may use these checkpoints.

Integrity, rights evidence, and split

Exit code is 0, FLUX2_KLEIN_LORA_COMPLETE is present, and all 57 entries in ALL_SHA256SUMS pass after local retrieval.
The exact model is black-forest-labs/FLUX.2-klein-base-4B revision a3b4f4849157f664bdbc776fd7453c2783562f4d; publisher code is 50fe5162777813d869182b139e83b10743caef15; official Diffusers is ec94eec6cabd536c44c77647038303e96ab9355b. Archived model, publisher, and Diffusers evidence records Apache-2.0.
Immutable config SHA-256 is 4e5445f90b9edf1eeb75b6a793d53c66c2100df66c00bc778ac27a8a98aefb84. The run used the official NF4 path because A100 compute capability 8.0 is below the official FP8 minimum of 8.9.
The corpus gate passed 32 exact 1024x1024 RGB normal fields from nine non-held-out slides at 0.25 micrometres/pixel. Metadata SHA-256 is 024754db101c6371b6e67f4f1247df921ab63b6ba618afcb2aa5c07578a2bf9a, provenance SHA-256 is 4d66a9d56dd9c9beef75fedebd3f69c7b04b8c4411a90f546048f585efab2831, and held-out manifest SHA-256 is 18377920a2dcca040e05ce875e4c7ecfe7a3f09d512539bf69d2eb681a26d0af.
Four whole rank-32 LoRAs were recovered at steps 32, 64, 96, and 128. Each is exactly 66,866,376 bytes. Their SHA-256 values are 708a08929835de9dc31c05b8123a21e19ef19b3a5a8ee31380597be952185f77, 1a26969574247af242ae49f99dee4c9207738be06533142b895c8a90eec78af7, ebd08e1442efd0edacaac952c6272fc69ff43ee59e2225bc456707c77838e776, and c52a17b5ac5a19f685600d8387c8b80d0f6e732d85a0a54a44dd733d5a225771.
Four fixed-seed validation images are exact 1024x1024 RGB PNGs. The six-cell real/zero-shot/checkpoint review sheet SHA-256 is a94c98966cb83123e87d281c17ae0674c27e732c35d39ead678566d4f440e714.

Privacy

Both preregistered screens pass. Against the corrected 32-field normal corpus, maximum DINO cosine is 0.845966 and minimum dHash distance is 21. Against the full corrected 128-field caption-neutral corpus, maximum DINO cosine is 0.845966 and minimum dHash distance is 21. Neither screen found an exact pixel match. DINO and dHash are privacy and nearest-neighbour checks, not clinical-quality evidence.

Whole-checkpoint engineering review

Step	Mean absolute gradient	Sydney-QA glands/mm2	Sydney-QA mucin/vacuole candidates/mm2	Block max cosine	Full-resolution result
32	2.999254	0.0	0.0	0.999986	Pale repetitive micro-rosettes and oversized circular pseudo-glands, without recognisable gastric foveolar or gland architecture; reject
64	3.077132	0.0	85.1	0.999972	Enlarged repeating radial rosettes and isolated white clefts; more conspicuous non-gastric topology than step 32; reject
96	3.523413	744.2	8,108.4	0.999875	Dense repeated oval/radial units and extreme clear-region surrogate count; no orderly local normal gastric topology; reject
128	4.215285	0.0	0.0	0.999594	Fine but nearly uniform nested ovals with strong pink/blue-channel saturation and no credible cellular or gland diversity; reject

All four checkpoints preserve or rearrange the zero-shot model's synthetic micro-rosette shortcut instead of converging toward the untouched M1 real normal field. Steps 32-64 add large radial structures; steps 96-128 collapse into dense, repetitive oval texture. The outputs lack credible nuclei, epithelial boundaries, lamina propria, and mixed-scale gastric glands. They are also visibly inferior to the already rejected Z-Image and Qwen controls in cellular detail. Sharpness increases modestly across checkpoints but cannot qualify structurally incorrect tissue.

Sydney-QA extracted raw and normalized stain, nuclei, gland/lumen, mucin/vacuole, inflammatory-surrogate, bacillus-surrogate, and repetition features plus audit masks for all four cells. Every record remains CALIBRATION_REQUIRED. The near-one block repetition scores and unstable classical segmentation are descriptive engineering warnings, not clinical grades. No GI-pathologist-annotated patient/slide-disjoint real envelope exists, so Sydney-QA cannot establish clinical correctness, diagnosis, Sydney grade, or OLGA/OLGIM and does not replace pathologist review.

Runtime, cost, and cleanup

The worker ran for 578 seconds. Conservative A100 instance uptime is 761 seconds, approximately US$0.78 at the project's US$3.673385/hour list-price assumption. The bounded e2-standard-4 recovery worker ran for 386.55 seconds, approximately US$0.01 at US$0.134/hour. Total conservative compute is below US$0.80 before temporary storage, credits, and tax; the A100 itself was Spot.

The A100 and recovery CPU are terminated. After complete local verification, the temporary recovery instance, read-only disk, and snapshot were deleted. The original stopped model disk remains retained.

Decision

No checkpoint advances. The failure is normal-gastric topology and category morphology, not integrity, privacy, rights-evidence capture, runtime, or GPU fit. The corrected Qwen, Z-Image, and FLUX.2 general-image LoRA routes have now each failed the same frozen normal-only gate. Another category-specific adapter on these backbones is not justified.

The next step is CPU-only: audit released pathology-native generators or pathology-specific super-resolution systems with an explicit submission-compatible model, code, and component licence chain. Any new GPU experiment requires a fresh normal-only preregistration against the same corrected split, untouched reference, privacy thresholds, Sydney-QA uncertainty, cost controls, and whole-checkpoint rule. Generic super-resolution remains ineligible because it can sharpen incorrect synthetic topology without restoring it.

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