{
  "file": "SGH_synthetic_03.png",
  "assigned_category": "H. pylori organisms with gastritis",
  "internal_category": "hpylori_gastritis",
  "sha256": "de17af691140b43b0f73beeb2548f559d6a12d31dc8fe69dfeb3feb18bea56cf",
  "width": 4096,
  "height": 2048,
  "mode": "RGB",
  "um_per_px": 0.25,
  "arm": "a5 match-si3",
  "package": "a5",
  "package_path": "[local]/a5",
  "run_id": "a5_p2_hpylori_gastritis_s12_across_match-si3",
  "source_png": "[local]/hpylori_gastritis_s12_across_match-si3.png",
  "source_sha256": "5427af84f32fe7e6751f434b31e9ed4b72ed8a4006056db6dacc3c3b0657e266",
  "cartoon_stem": "hpylori_gastritis_s12_across",
  "cartoon_set": "a1v2",
  "cartoon_seed": "12",
  "cut": "across",
  "provenance_class": "mosaic",
  "provenance_class_meaning": "A5 token_assignment: each of the 21 canvas windows drew its tokens from the real training window whose lumen mask best matched that part of the cartoon, so the canvas is conditioned on many real fields",
  "donor_fields": [
    "hiesd-4fdce538__hpylori_gastritis__76416_25728__mpp0.25.png",
    "hiesd-9ded7e41__hpylori_gastritis__7552_6976__mpp0.25.png",
    "hiesd-9ded7e41__hpylori_gastritis__21952_6848__mpp0.25.png",
    "hiesd-4769423f__hpylori_gastritis__22976_19008__mpp0.25.png",
    "hiesd-4fdce538__hpylori_gastritis__26624_18816__mpp0.25.png",
    "hiesd-28f9b423__hpylori_gastritis__10368_17152__mpp0.25.png",
    "hiesd-4769423f__hpylori_gastritis__85184_32704__mpp0.25.png",
    "hiesd-da8667dc__hpylori_gastritis__31616_6016__mpp0.25.png",
    "hiesd-9ded7e41__hpylori_gastritis__13504_5824__mpp0.25.png",
    "hiesd-324885ef__hpylori_gastritis__25984_9152__mpp0.25.png"
  ],
  "n_donor_fields": 10,
  "token_source": "token_assignment",
  "token_assignment_file": "[local]/hpylori_gastritis_s12_across.json",
  "token_assignment_sha256": "29d107c3e860e1fb9393973f3bae7364895bfb560812997094e5785302b01a53",
  "token_assignment_windows": 21,
  "token_assignment_donor_fields": 10,
  "token_patchbag_seed_base": null,
  "token_patchbag_library": null,
  "adapter_checkpoint": "",
  "adapter_sha256": "",
  "adapter_scale": null,
  "adapter_cond_channels": null,
  "adapter_label_groups": null,
  "label_map": "",
  "generator_seed": 51003,
  "start_index": 3,
  "steps": 20,
  "guidance_scale": 1.5,
  "windows": 21,
  "pass1_reference": "[local]/hpylori_gastritis_s12_across.png",
  "pass1_reference_sha256": "6098f177d4f136610820ac66a7cb702e563c88c01774839d50e46c65b8295c28",
  "parent_run_id": "",
  "parent_arm": "",
  "parent_seed": null,
  "parent_tokens": "",
  "instruments": {
    "envelope_D_mahalanobis": 4.985800905053995,
    "inside_heldout_band": 1,
    "pct_vs_heldout": 66.66666666666666,
    "ring_with_lumen_fraction": 0.4594594594594595,
    "ring_inside_real_range": 1,
    "ring_count": 74.0,
    "ring_density_per_mm2": 141.23766609210224,
    "median_ring_area_um2": 419.55555555555554,
    "laplacian_abs_mean": 19.008766174316406,
    "str_nuc_density_per_mm2": 1636.5268091246635,
    "nuc_density_per_mm2": 6475.937852033823,
    "nuc_area_median_um2": 22.22222222222222,
    "pale_tissue_fraction": 0.13962764152607934,
    "layout_iou_lumen": 0.04373758973575684
  },
  "screens_at_selection_time": {
    "_note": "the numbers the selection rule used, measured on the pre-overlay source PNG in its own package's evaluation; screens/ re-runs both screens on the ten final (post-overlay) files",
    "phikon_max_cosine": 0.8044310808181763,
    "copy_margin_0.95_minus_max": 0.14556891918182369,
    "ncc_max": 0.5258,
    "ncc_pairs": 2,
    "ncc_flagged_windows": 0,
    "own_source_fraction": 0.375
  },
  "window_seam_check": {
    "_note": "mean absolute horizontal gradient per column; value at the 1024-window boundaries (x=512,1024,...) divided by the median of the 32 columns around each, and the same statistic 256 px off-boundary as a null. Real held-out fields have no windows at all and sit at 0.948-1.005.",
    "at_window_boundaries_median": 1.0042768550858936,
    "off_boundary_null_median": 1.0350705140361605,
    "max": 1.0883377219060562
  },
  "real_heldout_reference_for_comparison": "hiesd-0d55cc29__hpylori_gastritis__118720_7424__mpp0.25.png",
  "eye_check": "Crowded epithelial cells with pale vacuolated cytoplasm and roughly one row of ovoid nuclei per group, a prominent cluster of red cells in the centre of the crop (a capillary or small haemorrhage), and small clear lumina at the lower edge. The stromal scatter is present but sparser than in images 01-02 (1637/mm2 against a real 4588), so the infiltrate that defines the category is thin. No seam (1.004 vs null 1.035) even though this canvas was assembled from many separate real donor fields.",
  "organisms": {
    "renderer": "research/sgh-synthetic-histopathology/scripts/pixcell_hp_stage.py --renderer surface",
    "renderer_version": "surface-mucus-v3",
    "seed": 7303,
    "requested": 90,
    "placed": 78,
    "sidecar": "[local]/SGH_synthetic_03__hp-stage-records.json",
    "pre_overlay_png": "[local]/SGH_synthetic_03__pre-overlay.png",
    "pre_overlay_sha256": "5427af84f32fe7e6751f434b31e9ed4b72ed8a4006056db6dacc3c3b0657e266",
    "surface_diagnostic": {
      "lumen_frac": 0.03883087635040283,
      "components": 27566,
      "max_component_px": 36187,
      "components_ge_20000": 1
    },
    "procedural": true,
    "note": null,
    "eye_check": "Cluster at (545,1865), 6 rods of 78 placed (12 short of the 90 requested; the canvas has one large lumen component of 36187 px). At 2x, a gland lumen bordered by dark basal nuclei is filled with rods. The density inside this single lumen is high - visually more organisms per lumen than the other three."
  },
  "publication_note": "Research candidate, not clinically verified. Local paths omitted; original image SHA-256 unchanged."
}